PreOp and PreOp HD  

Your trustworthy assistants for preoperative EEG analysis

  • Save time
  • Increase patient throughput
  • Consistent and objective reporting
  • Accurate source localization

Processing and interpreting EEG data and HD-EEG data can be very time-consuming and labor-intensive. Furthermore, purely visual EEG analysis does not allow a 3D estimate of the localization of epileptic discharges within the brain.

Based on more than 15 years of R&D experience, Epilog developed multi-center validated and CE approved EEG diagnostic technology. This technology is delivered through a cloud platform tailored to neurologists.




Our first product Epilog PreOp reduces time investment in analyzing long-term EEG recordings by offering automated spike detection. It adds extra information by including state-of-the-art 3D spike localization. The results are delivered through a concise and directly interpretable report and an online 3D viewer. EEG source localization will soon be one of the new standardized methods. With Epilog PreOp you have direct access to the best technology.

Link to Multi-center clinical study request  demo

Many centers are struggling analyzing their HD-EEG recordings due to software issues or a lack of time. Epilog PreOp HD is the way to go solution to efficiently analyze HD-EEG data that allows you to obtain the most from the data as possible.



Epilog Preop

Automated spike detection
Patient-specific source localization
3D viewer for preop evaluation


Discover how Epilog PreOp fits in your patient's journey

Screen for epilepsy

Does your patient has epilepsy?


Is the patient pharmacoresistant and considered for preoperative evaluation?

Pre-op evaluation

Long-term EEG monitoring
HD EEG monitoring

Epilog PreOp: Your trustworthy assistant for Pre-Operative EEG analysis

Seizure free?

Is the patient seizure free after surgery?

Post-op diagnostics

Was the epilepsy surgery successful?

A multi-center clinical study demonstrates that an epileptologist using Epilog PreOp can obtain a sensitivity and specificity of 80% and 75% respectively.

Try out epilog preop

For Whom

What is in it for you?


Preoperative EEG analysis in epilepsy patients is a time-consuming and labour-intensive process. Epilog PreOp offers an efficient alternative. Epilog automates the analysis of preoperative EEG data and provides the results in a concise report and 3D viewer with clear visualisation for preoperative evaluation.


The online Epilog platform provides researchers objective and consistent preoperative EEG analysis. The results are centralized on the Epilog PreOp platform and perfectly suited for further investigation.


The online Epilog platform can be accessed from anywhere in the world at any time. There are no hardware demands and it uses a simple, user-friendly interface making EEG analysis more efficient and time-saving than ever before.


Epilog used in clinical routine

Ghent University Hospital

At Ghent University Hospital patients go through an extensive work-up before the possibility of epilepsy surgery is discussed. All patients have long-term video-EEG-monitoring (usually 7 days), 3T MRI, FDG-PET and neuropsychological testing.

Geneva University Hospital

At the University Hospital of Geneva, the presurgical evaluation of refractory epilepsy patients contains a battery of clinical tests: structural MRI, video-EEG monitoring, interictal PET, ictal SPECT, neuropsychological examination, patient history and high-density EEG.



Epilog PreOp – FDA approved

New York, January 10th, 2018 - Epilog is excited to launch Epilog PreOp in the US market after receiving FDA clearance. Epilog PreOp is the trustworthy assistant for long-term EEG diagnostics and source localization during preoperative evaluation in epilepsy.

Epilog introduces Epilog PreOp HD

Epilog will introduce Epilog PreOp HD at AES in Washington in December 2017, Stay tuned.
PreOp HD

License agreement with University of Antwerp creates opportunities in fight against Alzheimer’s.

Biomedical start-up Epilog, a spin-off company of Ghent University and imec, also becomes a spin-off of UAntwerp. Both partners have plenty of ambition: their aim is to develop predictive biomarkers for Alzheimer's disease in the short term rather than the long term, enabling doctors to diagnose the disease much more quickly.

Discover the Epilog Academy

The Epilog Academy is a space where you can find presentations, blogposts and articles on automated EEG analysis and how it can be used to improve epilepsy diagnosis.
Epilog Academy

Tanja Hellier, our new VP Sales and Marketing

We can warmly welcome Tanja Hellier to our team. Tanja did her PhD in clinical neurosciences in Aachen, followed by a Post-Doctoral Scholar at the Department of Neurosurgery at the Medical University of South Carolina in Charleston where she is now a research assistant professor. Tanja is leading the US marketing and sales focusing on bringing direct diagnostic value to the patient.


22/8/2017. In today’s presurgical work-up, the patient is investigated with different neuroimaging techniques to identify the epileptogenic zone. The techniques that are included differ from center to center. Most centers perform video-EEG monitoring, MRI and interictal PET, but do not perform EEG source imaging to localize the epileptogenic zone. In this post, we discuss the added value of the different techniques and the advantages of including EEG source localization during phase 1 in your presurgical work-up.

Epilog PreOp Validation study published in Epilepsia Open

12/06/2017 - Our study on "Automated long-term EEG analysis to localize the epileptogenic zone" is now published in Epilepsia Open. 32 patients with refractory epilepsy were restrospectively analyzed to quantify the performance of our pipeline. Epilog PreOp reached a sensitivity of 80% and a specificity of 75%, which is higher than other techniques such as MRI, SPECT and PET routinely used for presurgical planning.