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Epilog’s Global Clinical Trial Services
De-risk your CNS trial with objective EEG parameters
Why?
EEG in CNS trials
Early stage
As sensitive parameters to characterize patient population and treatment, and evaluate efficacy.
Phase 2/3
As objective inclusion criteria and/or endpoints.
Phase 4
As validated biomarkers for further development and market access.
A holistic service and unique hybrid solution
Across all clinical trial stages
From natural history and pharmaco-EEG studies to biomarker research and validation. Supporting early to late pharmaceutical development for CNS pipelines with expert consulting and advanced analysis.
Driven by machine learning and brain power
Combining the sensitivity of automated EEG quantification, powered by AI, with the specificity and expertise of certified central readers. Standardized and centralized, for faster and more consistent results.
How?
4 steps to successfully apply validated EEG endpoints
- CONSULTING - Expert consulting on EEG protocols, pharmacometrics, and biomarker validation.
- COLLECTING - High quality and standardized EEG data collection, at home or in the hospital.
- PROCESSING - Central data collection and processing on secure cloud platform, combining AI and central reading.
- REPORTING - Statistical analysis of endpoints and data reporting.
“Considering EEG in the early stages of clinical development paves the way to validated EEG biomarkers.
Epilog brings a fresh perspective to the table, built on clinical, technical, and practical experience.”
Get in touch to discuss your upcoming trial.
Contact Eline
EEG parameters
Spikes and seizures
Count and localization of spikes and seizures. Evaluate EEG signals with electrical source imagining (ESI) to localize pathological signals.
Spectral and functional connectivity
Quantification of brain rhythms in the different frequency bands. Elucidate brain networks through functional connectivity analysis.
Sleep staging and efficiency
Nocturnal spike count per sleep stage, sleep spindle duration, spectral features, ...
More...
Get in touch to discuss tailor-made solutions for your clinical trial such as event-related potential (ERP) analysis and other advanced techniques for cognition and attention!