Your trustworthy assistant for long-term EEG diagnostics and source localization during the preoperative evaluation.

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Long-term preoperative EEG analysis in epilepsy patients is a time-consuming and labour-intensive process. This often leads to analysis backlogs. Epilog PreOp offers an efficient alternative.

Automated spike detection

Spikes are identified in the EEG recordings of your patients using FDA-approved / CE-marked algorithms.

3D patient-specific source localization

Six-layered head models are constructed from the MR image of your patient to localize the epileptic activity in the brain.

Concise online report and 3D viewer

The results are concisely summarized in a report with clear visuals and 3D viewer for optimal epilepsy diagnosis and treatment.

Epilog PreOp automates the analysis of preoperative EEG data and provides the results in a concise report with clear 3D visuals for optimal epilepsy diagnosis and treatment. The online Epilog platform can be accessed from anywhere in the world at any time. There are no hardware demands and it uses a simple, user-friendly interface making preoperative EEG analysis more efficient than ever before.


  • Saving time and resources
  • Increased patient throughput
  • State-of-the-art source localization
    >80% sensitivity
    >75% specificity
  • Consistent and objective reporting


Based on a large patient database we validated our spike detection and EEG source localization techniques on typical clinical long-term EEG recordings (27-32 electrodes). The results we obtained with Epilog PreOp are depicted on the left and show that advanced EEG analysis obtains higher sensitivity and specificity than MRI, SPECT and PET during the preoperative evaluation!


*Brodbeck et al., 2011, Brain

*van Mierlo, Strobbe et al., 2017, Epilepsia Open


Epilog is your partner supporting you with training, clear interpretation guidelines and cases that will improve your EEG analysis in clinical practice.

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Epilog PreOp used in clinical routine

Ghent University Hospital

At Ghent University Hospital patients go through an extensive work-up before the possibility of epilepsy surgery is discussed. All patients have long-term video-EEG-monitoring (usually 7 days), 3T MRI, FDG-PET and neuropsychological testing.

Geneva University Hospital

At the University Hospital of Geneva, the presurgical evaluation of refractory epilepsy patients contains a battery of clinical tests: structural MRI, video-EEG monitoring, interictal PET, ictal SPECT, neuropsychological examination, patient history and high-density EEG.