Your trustworthy assistant for long-term EEG diagnostics
and source localization during the preoperative evaluation.

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Electrical source imaging can provide valuable insights in the preoperative evaluation for refractory epilepsy. However, such advanced EEG analysis is a time-consuming and labour-intensive process. Epilog PreOp offers an efficient and clinically validated alternative.


Automated spike detection

Epilog PreOp uses accurate and clinically validated techniques for spike detection and clustering.

3D patient-specific source localization

A patient-specific head model that includes six tissue types (scalp, skull, CSF, air cavities, gray and white matter) is generated from your patient’s MRI. This dedicated model enables the most accurate localization of epileptic activity in 3D within the brain.

Concise online report and 3D-viewer

The results of the analysis are provided in a report that contains all relevant information. The reconstructed epileptic activity can also be visualized using our 3D viewer, or exported to the PACS system of your hospital.

Epilog PreOp comes in packages of slots you can use to process your patient data. When ordering a package, Epilog adds new slots to your account.  The prices vary depending on the number of slots you order. Please check our pricing to get to know more, or contact us for a tailor made contract.

Support & Guidelines

Click below to find the Epilog PreOp quick-guide, instructions for use, EEG data formats and requirements and report interpretation guidelines.


Patient specific MRI
Check a typical report
Patient specific MRI
Check a typical report
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The complete Epilog PreOp processing pipeline was validated on typical clinical long-term EEG recordings (27-32 electrodes). The results are depicted on the left and show that automated spike detection combined with electrical source imaging obtains higher sensitivity and specificity than MRI, SPECT and PET during the preoperative evaluation.


*Brodbeck et al., 2011, Brain

*P. van Mierlo et al. Automated long-term EEG analysis to localize the epileptogenic zone (2017). Epilepsia Open 2(3):322-333.


Epilog PreOp used in clinical routine

Ghent University Hospital

At Ghent University Hospital patients go through an extensive work-up before the possibility of epilepsy surgery is discussed. All patients have long-term video-EEG-monitoring (usually 7 days), 3T MRI, FDG-PET and neuropsychological testing.

Geneva University Hospital

At the University Hospital of Geneva, the presurgical evaluation of refractory epilepsy patients contains a battery of clinical tests: structural MRI, video-EEG monitoring, interictal PET, ictal SPECT, neuropsychological examination, patient history and high-density EEG.